My PSA score was only 4.7 (which isn't much over the threshold for my age) but I had cancer and it was quite advanced. However, quite high PSAs can be caused by other things, such as an enlarged but cancer-free prostate. Even exercising can raise the PSA level so if a test is arranged you shouldn't do vigorous exercise or have sex for at least 24 hours before.Sort of Warney. If a fella has a PSA of over 4 but less than X then a watching brief can be set up. Then it is the direction of travel of the PSA which becomes important. If, however, the PSA is significantly elevated then cancer will be strongly suspected and the scanning machine gets wheeled out.
So it isn’t really a false positive, as PSA levels are just a guide for next action: none, watching brief, scans.
You are right though, that because PSA is only a pointer to cancer on some occasions, using it as the basis of a screening programme would be pointless.
The saliva test you mention is interesting.
Personally, if offered "watchful waiting" I'd push for an MRI. If that then shows up minimal issues then waiting may be appropriate, especially for older men who may be more affected by the biopsy process.
But as I've been told numerous times on my PC journey, "everybody's different and what's best for one may not be best for another".





